Using MR, we tested the causal relationship between l-glutamine levels and painful crises in SCD patients.
We tested the association of a common *PIEZO1* variants with red blood cell density, hemolytic parameters, estimated glomerular filtration rate (eGFR), and SCD clinical complications.
We performed the first genome-wide association study for red cell density (DRBC) identify new genes involved in RBC hydration in SCD in 374 sickle cell anemia patients.
Designing a variant-aware library we investigated the role DNA regulatory elements.